If you are of a woman of childbearing age, do not use this medication unless you need a nonsteroidal anti-inflammatory drug (NSAID) such as diclofenac and you are at high risk of having an ulcer or ulcer complications from NSAID treatment.įemale patients must meet the following four requirements in order to use this drug: 1) test negative for pregnancy within 2 weeks before starting treatment 2) use effective birth control to prevent pregnancy 3) receive oral and written warnings on the dangers of using misoprostol while of childbearing age and the risks of possible birth control failure 4) start taking this medication only on the second or third day of the next normal menstrual period. If you become pregnant while taking this medication, contact your doctor right away. The risk for uterine rupture increases as your pregnancy advances and if you had prior uterine surgery (including Cesarean delivery) or if you had five or more previous pregnancies.Īvoid pregnancy while taking this medication and for at least one month or one complete menstrual cycle after you have stopped treatment. These problems have caused harm to the mother and unborn baby. In rare cases, serious problems (such as uterine rupture) have occurred when misoprostol was used to start labor or to end a pregnancy. Misoprostol may cause loss of pregnancy, premature birth, or birth defects. Do not take this medication if you are pregnant or think that you may be pregnant. This medication is a combination of 2 drugs: diclofenac and misoprostol.
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